Diabetic Eye Disease Overview

Diabetes mellitus is one of the leading causes of irreversible blindness worldwide, and, in the United States, it is the most common cause of blindness in people younger than 65 years of age.

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In addition to being a leading cause of blindness, diabetic eye disease encompasses a wide range of problems that can affect the eyes.

Diabetes mellitus may cause a reversible, temporary blurring of the vision, or it can cause a severe, permanent loss of vision.

Diabetes mellitus increases the risk of developing cataracts and glaucoma.

Some people may not even realize they have had diabetes mellitus for several years until they begin to experience problems with their eyes or vision. Severe diabetic eye disease most commonly develops in people who have had diabetes mellitus for many years and who have had little or poor control of their blood sugars over that period of time.

Diabetes mellitus may also result in heart disease, stroke, kidney failure, and circulatory abnormalities of the legs.

The American Diabetes Association estimates that 20 million people in the United States have diabetes. One-third of this population is unaware of their illness. A recent change in the exact definitions of diabetes and "pre-diabetes" by an international expert committee leads to the estimate that an additional 41 million people in the United States (40% of adults aged 40-74 years) have "pre-diabetes," a condition that significantly increases their risk for developing diabetes.
This new definition underscores the importance for everyone to take steps to help prevent the development of this disease. Individuals can try to avoid the problems associated with diabetes mellitus, including those that affect the eyes, by taking appropriate care of themselves by:

Maintain a normal weight

Watch your diet, especially limiting unhealthy types of fats and substituting complex carbohydrates for simple carbohydrates.

Participate in an exercise program, performing at least 2 1/2 hours of aerobic exercise very week.

Do not smoke

Lifestyle management has been shown to reduce the risk of developing type II diabetes and pre-diabetes by at least two-thirds. It can also slow or halt the progression of pre-diabetes to diabetes.

If you or someone you know has already been diagnosed with diabetes mellitus, the following steps should also be taken:

Monitor blood sugars and glycosylated hemoglobin. (The protein in the red blood cells that carry oxygen is called hemoglobin. Glycosylated hemoglobin is hemoglobin that has bonded to blood sugar.)

Take diabetes medications as prescribed by the healthcare provider.

Things You Should Know About Eye Diseases

Lucky for us there are many trained professionals who specialize in this particular area as there are so many eye diseases.

Sometimes these problems relating to eye occur due to eye strain or a person not taking proper care of his or her eye sight the way it is meant to be taken care of and there are even certain individuals who are genetically predisposed. Some of these eye diseases are curable while some are not as some can be stopped from advancing and some can even be totally reversed. If you are having any sort of problem relating to eye then the first thing you need to do is get you eyes examined and determine what sort if condition your eyes have and once you have determined that then you can take care of it accordingly.

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There are five eye diseases which are most common in effecting the eyes. The first one on them is known as Hyperopia which is more commonly termed as far sightedness. It is the kind of eye problem where the distant vision is clear but the eyes are unable to focus on close work. The major symptom of far sightedness is blurred vision when performing or dealing with close works like reading. Other symptoms of this eye disease include headache and eye strain. The eyeball in this case becomes shorter than it normally should be and therefore a deformation of the eye muscle takes place.


The second one of these major eye diseases is Myopia which is more commonly known as near sightedness. In this case the person is unable to see distant objects clearly and as a result different other problems arises because distortion of the eye ball takes place due to near sightedness and is exactly opposite to that of Hyperopia as the eyeballs lengthen more than they normally should. Cataract is the third one among these eye diseases and is usually considered to be related to aging as the eye becomes weaker with age and as a result naturally occurring proteins join together and make clumps which increase in size over time and begin to grow over the lens thus making the vision blurry.

Astigmatism is the fourth eye disease in which the cornea of a person ceases to be round in shape and becomes curved and as a result the vision is affected and it needs to be diagnosed by a specialist in order to be treated in the right manner. Glaucoma is the fifth one and is one of the most common eye diseases where a person loses peripheral vision due to damage of the optic nerves and it is also the main symptom of it. It is caused by the build up of fluid in the eye. It has the tendency to come on slowly thus a person does not realize that his vision is changing. So in order to protect ourselves from this disease one needs to get his eyes examined every two to three years so that it can be diagnosed even before symptoms of it occur.


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Walmart tries new tech with eye on consumers

Walmart could start letting shoppers buy products in the aisles and skip the checkout line, but the world's largest retailer needs to find out how that would improve the customer experience, the company's e-commerce chief said Thursday.

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With Apple's new EasyPay feature for its Apple Store iOS app, shoppers with an iPhone 4 or 4S can buy some products simply by scanning the barcode, entering their Apple ID, and walking out with the item. Venky Harinarayan, Walmart's senior vice president of global e-commerce and head of Walmart Labs, said the issue with setting up such a feature is not technology but the user experience.

"Yes, you can do this. ... What we've got to figure out is, how do you make that customer experience something really worthwhile," Harinarayan said. The same is true of other new technologies. "These are not technology problems, they are customer experience problems."

Walmart is also interested in NFC (near-field communication) for making purchases by phone and in setting up a social network among the shoppers in its stores. But the company has just begun to study how those could make Walmart a better place to shop, Harinarayan said. He appeared in an on-stage interview at the GigaOm Roadmap conference in San Francisco. Walmart Labs was established earlier this year in Mountain View, California, following the retailer's acquisition of Harinarayan's startup Kosmix, to try out these types of ideas, he said.

Walmart has high hopes for a blending of social media and shopping, Harinarayan said. At the corporate level, the company could use trend information from social-networking sites such as Facebook and Twitter to inform its product and distribution decisions. Walmart Labs is setting up a "big and fast data group" to explore ways to take advantage of the huge amounts of information it has about shopping behavior and combine it with social-networking data, he said.

For example, finding out when people in Wisconsin start mentioning college football in status updates could help the company decide when to start putting team merchandise on shelves in that state, he said. And decisions about what toys to sell during the year-end holiday season, which need to be made in February or March, prove more accurate if the company looked at what types of toys people were talking about at that time, he added.

Within brick-and-mortar stores, Walmart may eventually set up a mobile social-networking service of its own, where shoppers and sales associates all could post comments and questions that everyone in that store could see, Harinarayan said. "How will this work? We don't know. But it's a very interesting experiment for us," he said.

Walmart's online store could tap into social networking even more deeply, Harinarayan said. The company is trying to find the right way to take advantage of data on daily activity on online social services. That won't be simply by having a Facebook page where users can find and buy things, but through integrating shopping into the usual things Facebook users do, he said. An obvious way is with buying gifts, a naturally social activity. "Gifting is not done well today on the Web," Harinarayan said.

"This actually has been playing really, really well over the last few weeks as we've started engaging some of this," he said. Mining social-networking data "can impact billions of dollars of merchandise if we get it right," he added.

Walmart eventually would like to provide an API (application programming interface) and let third parties create applications using some of these capabilities, but it is still very early in the development process, Harinarayan said.

Harinarayan declined to give more details on Thursday about Walmart Labs' purchase of Australian startup Grabble, a developer of point-of-sale systems for mobile phones.

How to treat eye infection

There are different forms of eye infection, but the most common form is bacterial conjunctivitis which is a disease caused by bacteria. These germs can come from upper respiratory area or patient skin and can be caught from another person with conjunctivitis. During this infection there is chewy discharge due to which the lid attaches together particularly when the person gets up after sleeping. A patient has redness; swelling and irritation in eye and it typically affect one eye and can be extended to the other eye.

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Another form of eye infection is viral conjunctivitis which is related to common clod and sore throat. Its indications include irritation, itching, watery discharge and redness. The disease starts on one eye but may spread to the other eye. Allergic conjunctivitis is an eye infection whose common causes are other allergic syndromes like asthma, eczema and hay fever. Pollen, dust particles or cosmetics are some reason of this conjunctivitis. Its symptoms include itching, increased production of tears and swollen eyelids and it generally affects both eyes. Chemical conjunctivitis happens if some acidic or alkali substance gets into the eye. Some people are at risk to smoke, gases and chemicals in swimming pools. Its indications include irritation, pain, redness and watering.


Eye infections can happen in any age group of patients. Some eye infections can increase to severe disorders. Most eye specialists treat eye diseases in a hostile way. People who have suffered eye surgery or eye injuries are at higher risk of disease and some eye ailments are highly infectious so if someone has infection and you come across such person you are at a greater risk of becoming infected.
We can avoid eye infections by many ways. These ways include washing hands before and after touching your face or eyes and Avoid rubbing the eyes as this can increase infection. Do not use eye makeup until eye disease is fully treated. Do not share eye makeup, pillows and towels. Do not recycle handkerchief instead use tissue when needed. Do not swim as swimming pool contains some chemicals that can damage eyes. When working with chemicals put on safety glasses. Keep your eyes away from dirty water and protect your eyes from wind and heat.

We can treat eye infection and pain by applying a clean cloth soaked in lukewarm water to your eye for five minutes every two hours. Flaxseed can treat swelling, irritation and pain of eye. For 15 minutes heat flaxseed in 4 ounces of water and put this warm solution on cloth and apply it on eyes three times a day. Another home treatment for eye infection is Chamomile. For 15 minutes heat 3 cups of chamomile in 2 cups of water and wash eye with this mixture three times a day. Rose water is one of the simplest and best treatments for eye infection. Dip cotton in rose water and apply it on your eye for 15 minutes. Aloe Vera juice is also effective for eye infection take some Aloe Vera juice dip cotton in it and place it on the eye for 15 minutes. Carrot juice is very healthy and useful for curing eye infection. One more home remedy for eye infection is Ginger. Heat small piece of ginger in water dip cotton in this solution and apply it on the eye for some time it gives relief from itching and irritation.


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Eye Disease- Stye Problem

Eyes are organs that detect light, and send electrical impulses along the optic nerve to the visual and other areas of the brain. Some eye problems are minor and fleeting. But some lead to a permanent loss of vision. Common eye problems include:
Cataracts - clouded lenses
Glaucoma - damage to the optic nerve from too much pressure in the eye
Retinal disorders - problems with the nerve layer at the back of the eye
Conjunctivitis - an infection also known as pinkeye
Stye- A stye, or hordeolum, is a small bump that can appear on the outside or inside of the eyelid.

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A sty is an acute infection or inflammation of the secreting glands of the eyelid. A sty can also arise from an infected hair follicle at the base of an eyelash. It is sometimes referred to as a pigpen or pig parlor. Sties are usually areas of bare ground and / or mud. It is caused by bacteria that normally live peacefully on the surface of the eyelid skin. It is a red, painful swelling on the edge or inside of your eyelid that may look like a boil or a pimple. Also known as hordeolums, styes can be caused by different factors, such as blocked or infection or inflammation of the eyelid eyelids. Contaminated fingers that touch the eye area can also cause infection. The eyelid becomes sore. The infection can spread along the eyelid and the whole lid may become red and inflamed. If an internal Sty not drain and heal, it can turn into a Chalazion. A sty results from an acute infection of the oil glands of the eyelid that occurs after these glands have become clogged.

Causes of stable
Common causes and risk factors:
a) An infection in the sebaceous (oil producing) or sweat glands in the eyelid.
b) A Chalazion develops when an oil gland in the eyelid becomes blocked.
c) Using mascara, eyeliner, eye or other products that can irritate the eyes.
d) Rubbing eyes.
e) Symptoms stable

Here is a list of methods of treatment:
a) Most styes will drain on its own though this may be accelerated with a hot or warm compress.
b) Use makeup remover instead of just soap and water to remove eye make-up. This prevents heavy rubbing of your eyes and more completely removes the make-up.
c) Although antibiotics are often used to treat styes, they do not help much.
d) If a style or Chalazion is too large, the doctor may need to bid so that can drain and heal.
e) Paracetamol will also help relieve the pain of a sty.
f) A sty does not begin to improve after 3 days of home treatment or does not heal in a week.
g) Antibiotic ointments or eye drops may help cure the infection. If the skin around it is becoming infected, antibiotic pills may be needed.

Your best defense is to have regular checkups, because eye diseases do not always have symptoms. Early detection and treatment could prevent vision loss.

Sun Glasses for Fashion and Style

Sun Glasses are the most important part of fashion and style.

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Sunglasses protect your eyes from the harmful sun rays. This mostly use in summer and popular in girls and women as well. Stylish sunglasses are the important part of accessories for summer If you have no idea that what kind of sunglasses suits on you then take a look in photo gallery and apply the sun glasses according to your face shape and skin color. Choose the right style for your face.

Online Spectacles - Save Time & Money

When you buy glasses in the internet you can expect online spectacles to be a lot cheaper in price than in a traditional retail store. Buying online is a great alternative to the traditional methods of purchasing prescription spectacles. You also save a lot of time because you are not beholden to the hours of specs stores or have to worry about getting to them. Running around for glasses can be chaotic and a real pain in the neck. Shopping online takes that component of spec purchasing out of the picture.

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Online spectacles resellers provide the convenience of being able to shop at your leisure from your home or office. Access is twenty four hours seven days a week so you can be in control of when you go shopping for your new specs. If you want to go shopping at midnight in only your pajamas, go right ahead, it is all up to you. And, you can take your time while you are shipping with no one there to bother you the virtual store is all yours. You can review all the hundreds of different combinations of frames and lens right there on your computer screen. No need to rush so you can make an informed decision.

Online spectacles purchases are a good value too. You already know about all the savings involved by purchasing online, but do you also know what comes with each pair of specs? Every pair of prescription specs that you buy comes with features like, total UV protection, anti scratch coat, thin lens, edge polishing, a hard case and a cleaner cloth. And, just to make sure you stay happy with your online spectacle purchase, there is a guarantee as well. Therefore there is no reason not to buy your glasses online.

When you purchase spectacles online you alleviate all the hassle that goes into buying new specs and in fact can find the whole experience to be fun. Picking out new specs should be fun. They are not just important for seeing but they are also important for being seen. What you wear on your face is a reflection of your personality. The right pair of specs can say so many things about you. Nobody has to know you didn't pay a mint for them either. Let them think what they will about where your stylish new specs came from. Enjoy your specs.

Self-Adjustable Eyeglass Lenses

In developed countries, getting glasses is a simple matter: Visit an optometrist, get a prescription and have it filled at a corner store. Not so in the developing world, where there are few optometrists and little money for luxuries like eyeglasses.

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Enter Joshua Silver, an atomic physicist at Oxford with a penchant for tinkering. “I like to experiment,” he said. “Take things apart and figure out how they work.”

In the 1980s, he began a do-it-yourself project making lenses whose focusing power could be changed by the user. He designed and built a liquid-filled packet made of two flexible transparent membranes — a liquid lens. Adding or draining liquid changes the curvature, making the lens stronger or weaker.

“I realized after a few months that I could make a very good lens — good optically, but not for glasses,” Dr. Silver said. “I started some dialogue with the World Health Organization and found the director of the program for the prevention of blindness. I asked him how many people in the world needed glasses and don’t have them. He said it was about a billion.”

Working with a British government grant, Dr. Silver developed a practical pair of adjustable eyeglasses. The two lenses are filled with clear silicone fluid, and there is a dial on each arm. The user puts on the glasses and then twists each dial until vision in both eyes is satisfactory.

The glasses do not correct for astigmatism, Dr. Silver said. “Many people, if you just correct their spherical refractive error, you get vision good enough to function.”

The glasses are not beautiful. The thick frames resemble those worn by Jean-Paul Sartre. But the dial and pump can be removed after adjustment. More than 30,000 pairs are in use by adults worldwide, and a study financed by the World Bank is testing a version for use by teenagers.

Dr. Silver is director of the Center for Vision in the Developing World, and his goal is to see a billion people wearing the eyeglasses they need by 2020.

Signs and Symptoms of Eye Infections

Eyes may get infected due to reasons like infections or injuries. Generally eyes get affected by viral infections, bacterial infections and infection caused by other microorganisms. In most cases of eye infections bacteria and viruses are the main culprits. Fortunately there are certain medications and alternative therapies available for treating eye infections.

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signs and symptoms of eye infections.

1-Chronic redness of eyes
2-Frequent eye lid flanking
3-Itching
4-Blurring vision
5-Discomfort of eyes

Eye infections produce the sings and symptoms such as Chronic redness of eyes, frequent eye lid flanking, Itching, blurring vision, discomfort of eyes, watery eyes, pain in eyes, eye discharge, swollen eyelids and swollen eye surrounding tissues. The treatment of eye infections depends upon the symptoms and cause of infection.

Each individual may experience varying symptoms of eye infections. The most common sings and symptoms of eye infection include Chronic redness of eyes, frequent eye lid flanking, itching, blurring vision, discomfort of eyes, watery eyes, pain in eyes, eye discharge, swollen eyelids and swollen eye surrounding tissues. If you experience any one or group of above symptoms you must consult the doctor for immediate treatment.


There are also a number of herbal remedies that can speed your recovery and prevent a reoccurence of an existing eye infection. Bilberry is one of the most popular and it is known for it's ability to strengthen the capillaries in the eyes and heal a variety of eye conditions. It also works to prevent infections and diseases. Roobios and Sutherlandia Frutescens are powerful anti oxidants that help to ensure that your eyes are getting plenty of nutrients, blood and oxygen. This is essential to ensure that you heal quickly.

The bacterial eye infection is mainly caused by bacteria such as streptococci, haemophilus or the staphylococci bacteria. These bacteria are usually transmitted from one person who has the infection to another or sometimes the bacteria may come from the patient's own upper respiratory tract or skin where they are mostly situated.

There are many ways to treat them, depending on their severity. For minor eye infections like conjunctivitis, there are eye drops and ointments available from the pharmacist. These antibiotics kill the bacteria and prevent it from spreading any further. If not treated quickly, conjunctivitis can cause lasting damage to the cat's eye.


The infection occurs at the cornea which is responsible for most of the eye's optical power. Symptoms can include: blurred vision, pain and redness that does not improve when the contact lens is removed, increasing sensitivity to light, and excessive tearing or discharge. The condition if left untreated can lead to blindness or permanent vision problems.

Vitamin A deficiency can be a cause of swelling in the eyes of box turtles and a way you can treat this is to make sure you are introducing foods that are high in vitamin A as a part of your turtles diet every time you feed them. Foods such as Collard greens, carrots, kale and parsley all contain a good amount of vitamin A and can be added to each meal to help fight against this problem.

The iris is the colored portion of the eye. It can become infected and inflamed, due to various causes. When it is infected it becomes swollen, dull, and discolored. The pupil gets small, gray, and sluggish. There is pain, radiating to the forehead and to the temple, which is worse at night, and there is much disturbance of vision. In most infections of the eye the person who has an inflammation of the iris cannot stand to look at the light, and there is constant watering of the eye.

Alternative treatments for pinkeye in under developed countries include topical povidone-iodine (betadine) which is effective against most bacterial conjunctivitis at a fraction of the cost of standard antibiotic prescription eye drops. Povidone is sometimes used off label by optometrists to treat EKC, a special severe from of viral conjunctivitis.

Virtually all cats are exposed to Herpesvirus as kittens. For most cats, no further problems occur. However, Herpes is a sneaky virus, and it likes to lie dormant until it gets a chance to get one up on the immune system. Because stress suppresses the immune system, cats under stress are particularly susceptible to recurrent Herpes flare-ups.

Acanthamoeba infections are almost unknown in the United States in patients who replace their lenses daily or don't wear contact lenses. Hydrogen Peroxide contact lens cleaning systems kill the cyst form when used as directed. Chlorhexidine and heat systems will also kill the cyst form.

Eye Glasses- How To Choose Them

If we just think about the people who wear glasses and how their life would have turned out to be had they not been wearing those glasses? Some of the things that are essential for us these days would even not have been invented had it not been for eye glasses.

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With the invention of hard and soft contact lenses most people are under the impression that the need of eye glasses has decreased but it is not so a person who is habitual of wearing glasses cannot just switch to contact lenses and even if they do they would not be satisfied with them and there are even people who on the very thought of inserting two rubber flaps in and practically pasting them on your eyes get shivers. If people say that you cannot wear eye glasses to a party then they are wrong. If you have the right pair of glasses that go with your dress then you can not only pull of the glasses but can also get a lot of compliments. All you need to do is grab the right pair of eye glasses and you can then treat it as a fashion accessory for the party that you re going to but for that you need to know the right style and design of the eye glasses that goes well with your personality.

These eye glasses are available at different retail stores and you can find hundreds of designs with different colors and shapes. All you need to do is determine which glasses will suit you the best. You can even go shopping for them online and browse through the collection by sitting at your own place but the only draw back of that is that you cannot try them on. Nowadays there are some websites that offer the option of trying it on and all you need to do is upload your picture and you can see how they will look on your face.

If you have been diagnose with a particular eye condition that requires you to wear eye glasses there are certain things you must keep in mind when purchasing them. You must know that different conditions require different eye glasses hence reading glasses are different from permanent ones. So if you want to buy a pair of glasses for regular use the kind of eye glasses that you need to think about is a study pair while you can keep an expensive one just for special occasions. The lenses of the glasses need to be scratch resistant to provide a clear vision and if the glasses are meant to be used by a child then you must buy an inexpensive pair in case he breaks them.


Comfort is one of the most important things when dealing with eye glasses and the design and shape of the glasses needs to be of such nature that they neither sit too tight on the bridge of your nose leaving red scorched marks that make you look ugly nor should they be too lose. Loosing the eye glasses is really common in beginners, Frame suspenders that can be worn around your neck can help in this regard.

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Clear vision: Two principles for eye rejuvenation

Oriental Medicine teaches us that the opening of the liver channel is in the corner of the eyes. The liver channel runs vertically from the bottom to the top of the body and opens in the eyes. Whatever effects the liver also directly effects the eyes.

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The subtler functions of the liver root deeply into our emotional and psychic energies and thus the liver and our eyesight are impacted by excessive emotional stress. Any inflammation localized in the liver channel will cause inflammation of the eyes.

Therefore when we rejuvenate the liver, we directly promote the health of our eyes. The liver has a tremendous capability to rejuvenate itself. A healthy liver is soft and open. This softness permits the free flow of blood and energy to flow throughout the body directly to the eyes. A healthy liver keeps the blood clean and pure and thus directly improves eyesight. It is actually quite easy to rejuvenate the liver and thus rejuvenate our eyes.

As always, right diet is the foundation of all rejuvenation regimes. Raw organic greens which cleanse the blood and eliminate liver inflammation, should be used liberally And yes, carrots are good for the eyes so do enjoy your carrots. Beta carotene, one of the active ingredients in carrots, is also present in fresh green vegetable juices as well as green powder mixes. Along with beautiful fresh vegetables and grasses often found in green drink powder mixes, nature also provides an abundance of liver regenerating herbs such as burdock, taraxacum, barberry, scute, nettles, and more. Many of these herbs and grasses are combined into single liver cleansing products and they are effective and easy to use. There is tremendous healing potential contained in the synergy between the liver and these healing herbs. Consistent consumption of green plants and healing herbs promote eye health and contribute to our overall sense of well-being.

Things You Should Know About Eye Diseases

Lucky for us there are many trained professionals who specialize in this particular area as there are so many eye diseases.

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Sometimes these problems relating to eye occur due to eye strain or a person not taking proper care of his or her eye sight the way it is meant to be taken care of and there are even certain individuals who are genetically predisposed. Some of these eye diseases are curable while some are not as some can be stopped from advancing and some can even be totally reversed. If you are having any sort of problem relating to eye then the first thing you need to do is get you eyes examined and determine what sort if condition your eyes have and once you have determined that then you can take care of it accordingly.

There are five eye diseases which are most common in effecting the eyes. The first one on them is known as Hyperopia which is more commonly termed as far sightedness. It is the kind of eye problem where the distant vision is clear but the eyes are unable to focus on close work. The major symptom of far sightedness is blurred vision when performing or dealing with close works like reading. Other symptoms of this eye disease include headache and eye strain. The eyeball in this case becomes shorter than it normally should be and therefore a deformation of the eye muscle takes place.


The second one of these major eye diseases is Myopia which is more commonly known as near sightedness. In this case the person is unable to see distant objects clearly and as a result different other problems arises because distortion of the eye ball takes place due to near sightedness and is exactly opposite to that of Hyperopia as the eyeballs lengthen more than they normally should. Cataract is the third one among these eye diseases and is usually considered to be related to aging as the eye becomes weaker with age and as a result naturally occurring proteins join together and make clumps which increase in size over time and begin to grow over the lens thus making the vision blurry.

Astigmatism is the fourth eye disease in which the cornea of a person ceases to be round in shape and becomes curved and as a result the vision is affected and it needs to be diagnosed by a specialist in order to be treated in the right manner. Glaucoma is the fifth one and is one of the most common eye diseases where a person loses peripheral vision due to damage of the optic nerves and it is also the main symptom of it. It is caused by the build up of fluid in the eye. It has the tendency to come on slowly thus a person does not realize that his vision is changing. So in order to protect ourselves from this disease one needs to get his eyes examined every two to three years so that it can be diagnosed even before symptoms of it occur.


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